Thermogenic potentials of bone marrow adipocytes

نویسندگان

چکیده

Bone marrow adipose tissue (MAT) is a unique fat depot located in proximity to bone surfaces and exerts regulatory functions the skeleton. Recent studies have demonstrated that MAT responds changes whole-body energy metabolism, such as obesity anorexia nervosa, where expands, resulting deleterious effects on Interestingly, shares properties with both brown white tissues but exhibits distinct features regard lipid metabolism insulin sensitivity. reports addressed capacity of undergo browning, which could be an attractive strategy for preventing excessive accumulation within In this review, we summarize addressing browning phenomenon its regulation by number pathophysiological conditions. Moreover, discuss relationship between adaptive thermogenesis health. Understanding thermogenic potentials will delineate biological importance organ unravel potential improving health metabolism.

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ژورنال

عنوان ژورنال: Bone

سال: 2021

ISSN: ['8756-3282', '1873-2763']

DOI: https://doi.org/10.1016/j.bone.2020.115658